Discovery of Flowering Hormone (Florigen) Receptor and Its Crystal Structure
نویسندگان
چکیده
Florigen, a mobile floral induction protein, initiates the flowering process of activating floral identity genes. Many details of the molecular function of florigen remain unclear. In the present study, we found that the rice florigen Hd3a directly interacts with 14-3-3 (GF14) proteins, but not with the transcription factor OsFD1. We further determined the 2.4-Å crystal structure of a tripartite Hd3a-14-3-3-OsFD1 complex [1]. The determined crystal structure offers biological insights into 14-3-3 proteins and how they play a key role in mediating an indirect interaction between Hd3a and OsFD1. Our biochemical, biophysical, and physiological experiments using rice cultured cells and transgenic rice plants revealed that 14-3-3 proteins are intracellular receptors of florigen to activate floral identity genes.
منابع مشابه
Flowering time: From photoperiodism to florigen
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